Immune System?
Explain how the immune system acheives three of the following: 1. Provides an immediate nonspecific immune response 2. Activates T and B cells in response to an infection 3. Responds to a later exposure to the same infectious agent 4. Distinguishes self from nonself
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- 1.) Many Responses, but One, Often Not Considered, is The Alternate Pathway of Complement. 2.) Obviously, T and B Cells Have a Huge Repertoire, B Cells Initially Are Activated Though an Antibody-Antigen Interaction At the Membrane, T Cells Recognize a Piece of Antigen Processed By APCs, Though Their TCR and a MHC II Interaction (Th Cells), Subsequently, Depending On their Subtype (Th1 or Th2), May Elaborate Hormones (Cytokines) to Activate Other Mechanisms of Immune Response (CD8 and B Cells). 3. ) A Portion of T and B cells Differentiate into Long-Lived "Memory" Cells, to Quickly Respond to Very Similar Antigen, "Amnesic" (Sp?) response. 4.) The actual Mechanism is Unknown, but there is Selection of TCRs in the Thymus.
- Firstly your body uses its skin to stop pathogens from entering. Your body later uses a fever either increasing or decreasing the temperature of your body for many pathogens only can survive in limited temperatures. Next the b and t cell are activated. The macrophages, (white blood cells) start eating the pathogens and displaying the pathogens antigens on the body of the macrophage. This signals for the B and T cells. The B and T cells come along and the T cells either become memory T cells which take note of the pathogen and store it in the blood, so if this species of pathogen enters the body again it will be recognized. The T cells also turn into killer T cells which go and decimate the pathogen. The B cells either turn into memory B cells like the memory T cell or they turn into plasma B cells which produce antibodies. The antibodies attach onto the the antigens of the pathogen which weakens it and eventually kills it. If this pathogen ever enters the body again, the memory B and T cells will have had it stored in the blood so it will be recognized.
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